[ad_1] Children with coronavirus disease 2019 (COVID-19) sometimes develop multisystem inflammatory syndrome in children (MIS-C), which is associated with high morbidity. The underlying mechanism associated with T cells is described by the researchers in a new study published on the prepress server bioRxiv* in November 2020, in response to superantigen …
Read More »Spike-based DNA vaccine shows excellent protection against SARS-CoV-2 in a hamster model
[ad_1] A study conducted at the United States Army Research Institute of Infectious Diseases shows how a relatively simple full-length DNA vaccine against the spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can elicit a neutralizing antibody response in a animal model – even after a single shot …
Read More »Nafamostat mesylate initially reduces SARS-CoV-2 viral load in hamsters, according to study
[ad_1] The researchers found that nafamostat mesylate, when injected into the nasal cavity of Syrian hamsters, can reduce the initial viral load of SARS-CoV-2 in the nose. However, this effect was temporary and further tests are needed to determine clinically significant effects. The hunt group results are available on the …
Read More »Researchers use the machine learning algorithm to identify common respiratory pathogens
[ad_1] Reviewed by Emily Henderson, B.Sc.November 11, 2020 The ongoing global pandemic has created an urgent need for rapid tests that can diagnose the presence of the SARS-CoV-2 virus, the pathogen that causes COVID-19, and distinguish it from other respiratory viruses. Now, Common respiratory from Japan demonstrated a novel system …
Read More »COVID-19-associated pulmonary aspergillosis caused by aspergillus fumigatus
[ad_1] Caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), coronavirus disease 2019 (COVID-19) is primarily a lung disease, and a large percentage of patients with severe cases also have a bacterial infection or secondary fungal. In fact, about 25% of patients with severe acute respiratory distress syndrome (ARDS), and …
Read More »SARS-CoV-2 spike glycoprotein optimized for conditions found in human airways
[ad_1] Belgian and German researchers have shown how the glycoprotein peak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is fine-tuned based on human airway temperature and protease conditions, which in turn improves viral transmission and the consequent pathology. Their study is available on bioRxiv * prepress server. The rapid …
Read More »Identification of antibody-resistant SARS-CoV-2 spike protein mutations
[ad_1] Using a number of different monoclonal antibodies, the researchers determined several mutations in the SARS-CoV-2 spike protein that leads to resistance. Understanding these resistant mutations is important for the development of effective therapeutic strategies. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for the COVID-19 pandemic, infects host cells …
Read More »Mask use and social distancing considerably reduce the incidence of many diseases, including COVID-19
[ad_1] Reviewed by Emily Henderson, B.Sc.November 10, 2020 Measures to reduce the spread of COVID-19 through non-pharmaceutical interventions (NPIs) such as mask donning and social distancing are a key tool to combat the impact of the ongoing coronavirus pandemic. These actions have also greatly reduced the incidence of many other …
Read More »Aspirin to be tested as a potential COVID-19 treatment as part of the RECOVERY study
[ad_1] Confirmed cases for coronavirus disease 2019 (COVID-19) – caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have surpassed 50.8 million worldwide. As many countries begin to impose tighter blockades once again amid recurring cases, scientists are frantically trying to develop an effective treatment regimen for COVID-19 or antiviral …
Read More »ACE2 and TMPRSS2 are not the only viral receptors mediating the entry of SARS-CoV-2
[ad_1] Most vaccine research in the current 2019 coronavirus (COVID-19) pandemic has focused on the role of the angiotensin converting enzyme 2 (ACE2) receptor in mediating viral entry into the host cell. However, a recent study published on the prepress server bioRxiv* in November 2020 discovers the major role played …
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