[ad_1] With an end to the 2019 coronavirus disease (COVID-19) pandemic in sight, the potential new reservoirs of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in animal populations are closely monitored. A new study published in the journal Science in November 2020 describes the probable transmission of the virus between …
Read More »Promising SARS-CoV-2 N epitope for more accurate diagnostic and surveillance testing
[ad_1] The 2019 coronavirus disease (COVID-19) pandemic calls for better and faster tests to ensure more accurate diagnosis, monitoring and surveillance of the disease and its spread. Serological testing is used to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection after the acute phase. A new study published on …
Read More »Research shows a unique repertoire of T cell receptors in MIS-C patients
[ad_1] Children with coronavirus disease 2019 (COVID-19) sometimes develop multisystem inflammatory syndrome in children (MIS-C), which is associated with high morbidity. The underlying mechanism associated with T cells is described by the researchers in a new study published on the prepress server bioRxiv* in November 2020, in response to superantigen …
Read More »Spike-based DNA vaccine shows excellent protection against SARS-CoV-2 in a hamster model
[ad_1] A study conducted at the United States Army Research Institute of Infectious Diseases shows how a relatively simple full-length DNA vaccine against the spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can elicit a neutralizing antibody response in a animal model – even after a single shot …
Read More »Nafamostat mesylate initially reduces SARS-CoV-2 viral load in hamsters, according to study
[ad_1] The researchers found that nafamostat mesylate, when injected into the nasal cavity of Syrian hamsters, can reduce the initial viral load of SARS-CoV-2 in the nose. However, this effect was temporary and further tests are needed to determine clinically significant effects. The hunt group results are available on the …
Read More »Parents normalize children’s symptoms to rule out COVID-19, according to a study
[ad_1] The current 2019 coronavirus pandemic (COVID-19) continues to spread around the world, with a resurgence of new cases reported in many countries. Overall, the toll of the COVID-19 case exceeded 51.37 million, with over 1.27 million deaths. These numbers are expected to increase further in the coming weeks as …
Read More »COVID-19-associated pulmonary aspergillosis caused by aspergillus fumigatus
[ad_1] Caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), coronavirus disease 2019 (COVID-19) is primarily a lung disease, and a large percentage of patients with severe cases also have a bacterial infection or secondary fungal. In fact, about 25% of patients with severe acute respiratory distress syndrome (ARDS), and …
Read More »SARS-CoV-2 spike glycoprotein optimized for conditions found in human airways
[ad_1] Belgian and German researchers have shown how the glycoprotein peak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is fine-tuned based on human airway temperature and protease conditions, which in turn improves viral transmission and the consequent pathology. Their study is available on bioRxiv * prepress server. The rapid …
Read More »Identification of antibody-resistant SARS-CoV-2 spike protein mutations
[ad_1] Using a number of different monoclonal antibodies, the researchers determined several mutations in the SARS-CoV-2 spike protein that leads to resistance. Understanding these resistant mutations is important for the development of effective therapeutic strategies. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for the COVID-19 pandemic, infects host cells …
Read More »Using sewage epidemiology to monitor SARS-CoV-2 in Houston
[ad_1] With cases of coronavirus disease (COVID-19) skyrocketing around the world, understanding the full extent of the pandemic is of paramount importance. However, it is an ongoing challenge for public health officials. Currently, diagnostic testing capacity may be insufficient, and in some hospitals, reporting of COVID-19 patients is delayed for …
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