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A new study from Tel Aviv University (TAU) and Shamir Medical Center in Israel shows that hyperbaric oxygen therapy (HBOT) among healthy adults can stop the aging of blood cells and reverse the aging process.
From a biological standpoint, adult blood cells also rejuvenate as treatments progress, the researchers say.
They claim to have discovered a unique protocol for oxygen treatments in a hyperbaric chamber, which can reverse two of the main processes associated with aging and disease: the shortening of telomeres (protective regions at both ends of each chromosome) and the accumulation of old cells in the body. .
The study focused on immune cells containing DNA obtained from the subjects’ blood, finding a telomere elongation of 38% and a decrease of 37% in the presence of aged cells.
“Our team has been involved in hyperbaric research and treatment for many years – treatments based on protocols of exposure to high pressure oxygen at different concentrations within a hyperbaric chamber,” said Professor Shair Efrati of Sackler University. of Medicine and director of the hyperbaric medicine department at Shamir Medical Center.
“In this study, we wanted to examine the impact of HBOT on healthy older adults and find out if such treatments can slow, stop or even reverse the normal aging process at the cellular level.”
The researchers exposed 35 healthy individuals over the age of 64 to a series of 60 hyperbaric sessions over 90 days.
Blood samples were taken from each participant before the start of treatment, during treatment, and at a time after the end of the sessions.
The researchers then analyzed the various immune cells in the blood and compared the results.
The results indicated that the treatment succeeded in reversing the aging process in two main aspects: telomeres at the ends of chromosomes lengthened by 20-38% instead of shortening, and the percentage of aging cells decreased between 11 and 37%, depending on the type of cell.
‘Telomere shortening is currently considered the’ Holy Grail ‘of the biology of aging,’ says Professor Efrati.
“Researchers around the world are trying to develop pharmacological and environmental interventions that allow telomere elongation. Our HBOT protocol has succeeded in doing this, demonstrating that the aging process can be reversed at the cellular-molecular level.” , Efrati stressed.
“Three months of HBOT treatment managed to lengthen telomeres at speeds far beyond what is currently available through lifestyle interventions,” said Dr. Amir Haddani, study co-author and medical director in the hyperbaric medicine department. by Shamir Medical Center.
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