[ad_1] Researchers have discovered a mysterious gene in the genetic code of the SARS-CoV-2 coronavirus, a segment virtually hidden from view in the virus genome and largely overlooked until now. The newly identified gene – called ORF3d – is an example of what is called an overlapping gene: a kind …
Read More »Discovering new genomes from terrestrial microbiomes
[ad_1] The artist’s interpretation of how microbial genome sequences from the GEM catalog can help fill knowledge gaps about the microbes that play key roles in Earth’s microbiomes. (Credit: Zosia Rostomian / Berkeley Lab) Despite advances in sequencing technologies and computational methods over the past decade, researchers have discovered genomes …
Read More »Identification of antibody-resistant SARS-CoV-2 spike protein mutations
[ad_1] Using a number of different monoclonal antibodies, the researchers determined several mutations in the SARS-CoV-2 spike protein that leads to resistance. Understanding these resistant mutations is important for the development of effective therapeutic strategies. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for the COVID-19 pandemic, infects host cells …
Read More »Scientists have just discovered 12,000 new species of microbes
[ad_1] Growing microbes in a petri dish is pretty simple – dab just about anything, wipe it on an agar plate, let it sit for a few days in a warm room, and presto! You raised new furry friends. But the microbial species you can grow in a petri dish …
Read More »New Zealand case study shows room for improvement in genomic sequencing of COVID-19 outbreaks
[ad_1] Researchers in New Zealand, the United States and Australia have demonstrated the effectiveness of real-time genomic sequencing in monitoring the reappearance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in New Zealand in August this year. . SARS-CoV-2 is the agent responsible for the current 2019 coronavirus pandemic (COVID-19) …
Read More »New insights into a common protein could have broad biomedical applications
[ad_1] Reviewed by Emily Henderson, B.Sc.November 4, 2020 A new study from the University of Colorado Boulder sheds light on a protein key to controlling how cells grow, proliferate and function and have long been implicated in tumor development. The results, published this week in the journal Genes and development, …
Read More »The study reveals the complex and vast diversity of African genetic variation
[ad_1] Reviewed by Emily Henderson, B.Sc.October 29, 2020 The study, in which six Wits researchers were involved, shows that these newly discovered variants were found mainly among newly sampled ethnolinguistic groups. Researchers identified new evidence for natural selection in and around 62 previously unreported genes associated with viral immunity, DNA …
Read More »Genetic analysis with RNA sequencing can increase diagnostic yield, the study shows
[ad_1] Reviewed by Emily Henderson, B.Sc.October 28, 2020 In the world of rare genetic diseases, exome and genome sequencing are two powerful tools used to make a diagnosis. A recent addition to the toolkit, RNA sequencing, has been shown to help researchers narrow down the candidate disease variants first identified …
Read More »The study investigates the link between clonal hematopoiesis and treatment-related blood cancer risk
[ad_1] Reviewed by Emily Henderson, B.Sc.October 27, 2020 In recent years, improvements in cancer therapy have led to a significant increase in cancer survival. Experts estimate that by 2022 the United States will have 18 million cancer survivors, but a subset of these survivors will have long-term health problems to …
Read More »Results of the Phase 1 trial of the gorilla adenovirus vaccine for COVID-19
[ad_1] A recent study published on the prepress server bioRxiv* in October 2020 reports the development of a new vaccine based on a simian adenoviral vector obtained from a group C gorilla isolate called GRAd32. This could help accelerate vaccine development. Low seroprevalence for simian adenoviruses Monkey adenoviruses are isolated …
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