[ad_1] Researchers studied the effect of several SARS-CoV-2 mutations on its binding to the human angiotensin 2 converting enzyme using molecular dynamics simulations. They found that the N439K mutant binds more strongly than the original Wuhan strain, which could have implications for therapies such as monoclonal antibodies. The 2019 coronavirus …
Read More »Pomegranate peel extract shows potential SARS-CoV-2 virus inhibitor
[ad_1] Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which causes COVID-19 (coronavirus disease 2019) has infected over 58.5 million people worldwide and killed over 1.38 million is one of the health crises most significant global in recent memory. There are currently no effective and safe vaccines to prevent SARS CoV-2 …
Read More »COVID-19 potentially has negative impacts on male fertility
[ad_1] A review recently posted on Journal of Medical Virology discussed some of the effects infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent that causes coronavirus disease 2019 (COVID-19), can have on male fertility. In the paper, Cemile Seymen of the Gazi University Institute of Health Sciences, …
Read More »Nafamostat mesylate initially reduces SARS-CoV-2 viral load in hamsters, according to study
[ad_1] The researchers found that nafamostat mesylate, when injected into the nasal cavity of Syrian hamsters, can reduce the initial viral load of SARS-CoV-2 in the nose. However, this effect was temporary and further tests are needed to determine clinically significant effects. The hunt group results are available on the …
Read More »Identification of antibody-resistant SARS-CoV-2 spike protein mutations
[ad_1] Using a number of different monoclonal antibodies, the researchers determined several mutations in the SARS-CoV-2 spike protein that leads to resistance. Understanding these resistant mutations is important for the development of effective therapeutic strategies. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for the COVID-19 pandemic, infects host cells …
Read More »ACE2 and TMPRSS2 are not the only viral receptors mediating the entry of SARS-CoV-2
[ad_1] Most vaccine research in the current 2019 coronavirus (COVID-19) pandemic has focused on the role of the angiotensin converting enzyme 2 (ACE2) receptor in mediating viral entry into the host cell. However, a recent study published on the prepress server bioRxiv* in November 2020 discovers the major role played …
Read More »Key to innate immunity to limit viral load in COVID-19 cases
[ad_1] As the 2019 coronavirus disease (COVID-19) pandemic continues to cause many difficulties for public health authorities, research is underway to understand how the virus can cause fatal effects on infected people and thus suggest effective preventive and therapeutic measures against it. . A new study by researchers from Houston …
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