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Tourcoing hospital is coordinating a “long Covid” study, which could eventually include 1,000 patients across France. The goal of this study is toidentify the causes of persistent symptoms in some patients, sometimes months after the acute phase of the disease.
Entitled “Cocolate”, for coordination on late covid, this study is currently underway, including its first patients, explains its coordinating physician, Dr. Olivier Robineau, from CH Dron’s infectious disease department. “The idea is that the study will gradually extend to at least 20 hospitals” and follows about 1,000 patients, he explains, noting that he is, as far as he knows, “the only study reported as an attempt to recover patients across the country“.
At least one persistent symptom
These patients who did not have a very severe form of Covid-19 and were not admitted to intensive care, will have in common to suffer at least one symptom that persists two months after the acute episode of illness. They will be referred by their primary care physicians to hospitals, who will offer them a coordinated path to explore their symptoms and can include them in the study.
Tiredness, shortness of breath, feeling of psychic slowdown, difficulty concentrating with the impression of being “in the fog“, Headache, joint or chest pain: persistent symptoms are quite numerous but”not very specific», Emphasizes Dr. Robineau.
The study will have to define the symptoms that may really be associated with persistent Covid, which today does not have “medical definition because we do not yet have sufficient reliable epidemiological data“.
Hypothesis about the causes of these symptoms it extends from the psychological field, with somatization linked to the stress of the epidemic, to the persistence of an inflammatory reaction, or even to the persistence of the virus. “All we want is to be able to say that Covid, in 90% of cases, stops in less than 3 weeks a month and that in some people it will last six months or a year, but that afterwards, people will be fine.“, He hopes, pointing out that mononucleosis or cytomegalovirus can tire for even six months, without there being any concern for the patient.
A study also launched at AP-HP
On the same theme of the long Covid, also AP-HP (Paris Hospitals) announced on Thursday the start of the second phase of a research project, after the one it has “identified 50 manifestations of these long forms thanks to the analysis of the experiences of 600 patients“.
And now “develop a questionnaire that allows to obtain a valid and reliable measurement of the long-term evolution of Covid“, who “could be used as a monitoring tool by caregivers in order to adapt their management based on symptoms and the impact of the disease on their lives and as an endpoint reported by patients in future research on the disease», Detailed the AP-HP, inviting them to register on the patient community site for research compare.aphp.fr
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