[ad_1] The 2019 coronavirus disease (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to a serious global public health crisis. To date, the virus has infected 63.75 million people and has caused the deaths of over 1.47 million worldwide, showing that there is an urgent …
Read More »A large-scale tool to study the function of autism spectrum disorder genes
[ad_1] Scientists at Harvard University, the Broad Institute of MIT and Harvard and MIT have developed a technology to study the function of many different genes in many different cell types at once, in a living organism. They applied the method on a large scale to study dozens of genes …
Read More »Researchers develop a defective synthetic SARS-CoV-2 genome that inhibits viral replication
[ad_1] A shorter genome comprising only part of the SARS-CoV-2 RNA genome competes with the normal virus for growth and can potentially prevent viral replication. The devastating impact of the 2019 coronavirus disease (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to significant efforts to …
Read More »The digital hot start CRISPR assay enables the sensitive quantitative detection of SARS-CoV-2 in clinical samples
[ad_1] In a recent medRxiv * preprint paper, the researchers of the Health Center of the University of Connecticut in the United States reveal their method CRISPR (WS-CRISPR) with digital hot start for rigorous quantitative and sensitive detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV -2) in clinical samples …
Read More »Genetic variations of SARS-CoV-2 transmission in cats
[ad_1] Using cats as an animal model to study the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the researchers determined that the virus has a narrow transmission bottleneck. The current 2019 coronavirus (COVID-19) pandemic, caused by the agent SARS-CoV-2, is widely believed to be zoonotic in origin (meaning …
Read More »The CRISPR / Cas9 system is highly effective in the treatment of metastatic cancers
[ad_1] Reviewed by Emily Henderson, B.Sc.November 19, 2020 Tel Aviv University (TAU) researchers have shown that the CRISPR / Cas9 system is highly effective in treating metastatic cancers, a significant step on the road to finding a cure for cancer. Researchers have developed a new lipid nanoparticle-based delivery system that …
Read More »The computational method could predict the immunotherapy response in patients with advanced melanoma
[ad_1] Reviewed by Emily Henderson, B.Sc.November 18, 2020 Conclusion: A computational method that combines clinicodemographic variables with in-depth learning of pre-treatment histological images could predict the response to immune checkpoint blockade among patients with advanced melanoma. Journal in which the study was published: Clinical Cancer Research, a journal of the …
Read More »Spike-based DNA vaccine shows excellent protection against SARS-CoV-2 in a hamster model
[ad_1] A study conducted at the United States Army Research Institute of Infectious Diseases shows how a relatively simple full-length DNA vaccine against the spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can elicit a neutralizing antibody response in a animal model – even after a single shot …
Read More »Nafamostat mesylate initially reduces SARS-CoV-2 viral load in hamsters, according to study
[ad_1] The researchers found that nafamostat mesylate, when injected into the nasal cavity of Syrian hamsters, can reduce the initial viral load of SARS-CoV-2 in the nose. However, this effect was temporary and further tests are needed to determine clinically significant effects. The hunt group results are available on the …
Read More »Scientists have just found a “mysteriously hidden gene within a gene” in SARS-CoV-2
[ad_1] Researchers have discovered a mysterious gene in the genetic code of the SARS-CoV-2 coronavirus, a segment virtually hidden from view in the virus genome and largely overlooked until now. The newly identified gene – called ORF3d – is an example of what is called an overlapping gene: a kind …
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