[ad_1] In an article recently published on Trends in endocrinology and metabolism, Graziano Pinna of the University of Illinois at Chicago outlines some of the evidence that suggests that female reproductive hormones may play a role in the sexual bias that has been observed in coronavirus disease 2019 (COVID-19). Reports …
Read More »SARS-CoV-2 N439K mutation may be more infectious and resistant to antibodies than Wuhan strain
[ad_1] Researchers studied the effect of several SARS-CoV-2 mutations on its binding to the human angiotensin 2 converting enzyme using molecular dynamics simulations. They found that the N439K mutant binds more strongly than the original Wuhan strain, which could have implications for therapies such as monoclonal antibodies. The 2019 coronavirus …
Read More »Body mass index and severe COVID-19
[ad_1] The COVID-19 pandemic has affected over 60 million people worldwide, of which nearly 1.43 million have died from the severe COVID-19 disease and nearly 40 million have recovered. COVID-19 disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is severe and leads to life-threatening complications in a small …
Read More »Researchers uncover blood gene signatures that can predict COVID-19 severity
[ad_1] A team of US scientists from the University of Chicago, NCH Healthcare System, and University of South Florida has identified a specific set of genes associated with a poor prognosis for coronavirus disease 2019 (COVID-19). The study is currently available on bioRxiv* prepress server. Severe acute respiratory syndrome coronavirus …
Read More »Researchers develop a defective synthetic SARS-CoV-2 genome that inhibits viral replication
[ad_1] A shorter genome comprising only part of the SARS-CoV-2 RNA genome competes with the normal virus for growth and can potentially prevent viral replication. The devastating impact of the 2019 coronavirus disease (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to significant efforts to …
Read More »A Review of Traditional Chinese Herbal Medicine in the Management of COVID-19
[ad_1] The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than 59.65 million people worldwide and caused the deaths of over 1.4 million. The virus, first detected in late December 2019 in Wuhan, China, is the most significant public health problem since the 1918 …
Read More »The digital hot start CRISPR assay enables the sensitive quantitative detection of SARS-CoV-2 in clinical samples
[ad_1] In a recent medRxiv * preprint paper, the researchers of the Health Center of the University of Connecticut in the United States reveal their method CRISPR (WS-CRISPR) with digital hot start for rigorous quantitative and sensitive detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV -2) in clinical samples …
Read More »Penn State researcher to study how vitamin D regulates host immunity to viral infections
[ad_1] Reviewed by Emily Henderson, B.Sc.November 24, 2020 Funding from the National Institutes of Health will allow a Penn State researcher to investigate whether vitamin D supplementation could help people ward off or reduce symptoms caused by COVID-19. Margherita Cantorna, a distinguished professor of molecular immunology and nutrition at the …
Read More »Biosensor Testing SARS-CoV-2 Antibody Testing Can Predict COVID-19 Severity in Patients
[ad_1] The 2019 coronavirus disease (COVID-19) pandemic continues to spread around the world, causing over 59.17 million confirmed infections and over 1.39 million deaths. The causative agent, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in Wuhan, China in December 2019. Understanding the size of the virus and its prevalence …
Read More »Favorable clinical outcome for ivermectin in the COVID-19 animal model
[ad_1] The coronavirus disease (COVID-19) pandemic, caused by severe acute respiratory syndrome (SARS-CoV-2), has caused more than 59 million cases globally. There is currently no vaccine or drug approved for the infection. However, doctors and scientists are using repurposed drugs to help hospitalized patients recover faster and improve clinical outcomes. …
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