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A scientific study found that mouthwash is capable of killing COVID-19 within 30 seconds of exposure to it in a laboratory.
These preliminary results, which have yet to be peer-reviewed, precede a clinical study investigating whether over-the-counter mouthwash can reduce levels coronavirus in the saliva of a patient.
The research, which was conducted at Cardiff University found that mouthwashes containing 0.07% of the ingredient cetypyridinium chloride (CPC) showed “promising signs” of reduction COVID-19.
A clinical study will examine the effectiveness of using mouthwash to reduce COVID-19 viral load among patients
These findings support another recently published study that identified CPC-based mouthwashes to be effective in reducing coronavirus viral load.
Scientists conducted tests in a laboratory mimicking the conditions of a person’s nasopharynx and oropharynx passages, using mouthwash brands like Dentyl.
A 12-week clinical trial at the University Hospital of Wales will now help determine the effectiveness of mouthwash in reducing COVID-19 viral load in patients’ saliva.
Dentyl will be the UK’s only mouthwash brand used in the trial, and the results will be published in early 2021.
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Professor David Thomas, of Cardiff University who is conducting the clinical trial, said: ‘While this in vitro study is very encouraging and a positive step, more clinical research is clearly needed now.
“We need to understand if the effect of over-the-counter mouthwashes on the laboratory-derived COVID-19 virus can be reproduced in patients and we look forward to completing our clinical trial in early 2021.”
Dr Nick Claydon, a specialist periodontist, said the research was “very valuable”.
He said: “If these positive results are reflected in the Cardiff University clinical trial, CPC-based mouthwashes such as Dentyl used in the in vitro study could become an important addition to people’s routine, along with hand washing, l ‘physical distancing and the use of masks, both now and in the future. “
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