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Despite repeated contact with his positive and symptomatic parents, this child never tested positive for Covid-19, never had symptoms, and developed stronger immunity.
In children, infection with SARS-CoV-2 often results in an absence of symptoms or a mild or moderate form of the disease. Severe forms in children are extremely rare. However, if they have been infected, they test positive like everyone else for the SARS-CoV-2 test. In an Australian family, despite repeated contact with his positive and symptomatic parents, a young child never tested positive for SARS-CoV-2 and never suffered from symptoms from COVID-19. Even more surprisingly, he developed a immunity stronger. Subject of study is published in the journal Nature.
A family case study
In the environmental recklessness of the previous world, this child’s parents returned home after being invited to a wedding. Upon their return, they suffered from cough, nasal congestion, temperature and headache: classic symptoms moderate Covid-19. From that point on, the entire family was recruited fromMurdoch University Children’s Research Institute (MCRI), in Victoria, Australia, to participate in a case study.
Parents and children all underwent clinical, virological, cellular, immune and serological tests together. Immune profiles at the cellular level as well as the cytokine response were similar at all stages in parents and children. Similarly, the amount ofimmunoglobulins A (IgA), first-line immunity was strictly identical in all family members. But, in one of the children, a more robust immunity developed, involving immunoglobulin G (IgG), similar to that of infected people (here in this case, the parents).
Important results for better understanding
Faced with these results, the authors conclude: ” These data indicate that children can develop immune response to SARS-CoV-2 without virologic confirmation of infection, increasing the possibility that immunity in children may prevent the establishment of SARS-CoV-2 infection. Relying on routine virological and serological testing may not identify exposed children, with implications for epidemiological and clinical studies throughout life. “
However, this study remains a case study and will need to be confirmed by other experiences. However, these findings are troubling and should be contested the scientific community. The associate professor MCRI’s Nigel Crawford, who oversaw the study, says: ” Studying immune responses to SARS-CoV-2 in all age groups is essential to understand disease susceptibility, differences in severity and the vaccines candidates. “
What you need to remember
- An Australian family was infected with SARS-CoV-2.
- He participated in a study to investigate a plethora of physiological characteristics in family members.
- In the batch, one child never tested positive for SARS-CoV-2, never suffered from Covid-19 symptoms but still developed robust immunity.
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