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A scientific study found that mouthwash can eradicate coronavirus within 30 seconds of exposure to it in the laboratory.
The preliminary result comes before a clinical study to evaluate whether the use of an over-the-counter mouthwash has the potential to reduce Covid-19 levels in a patient’s saliva.
The Cardiff University report says mouthwashes containing at least 0.07% cetypyridinium chloride (CPC) have shown “promising signs” of being able to fight the virus.
The report – Virucidal efficacy of oral rinse components against SARS-CoV-2 in vitro – has yet to be peer-reviewed, but it supports another study published last week that found CPC-based mouthwashes to be effective in reduce the viral load of Covid.
The latest test was performed by scientists from the university’s lab and mimicked the conditions of a person’s nose / oropharynx passage using brands of mouthwash including Dentyl.
A clinical study will then examine the effectiveness of mouthwash in reducing the viral load in the saliva of patients with Covid-19 at the University Hospital of Wales in Cardiff, the results of which are expected to be published in the first part of 2021.
Dentyl is the only UK brand of mouthwash to take part in the 12-week clinical trial, led by Professor David Thomas of Cardiff University, entitled: “Measuring the antiviral activity of mouthwash against Covid-19”.
Dr. Thomas told the PA news agency: “While these mouthwashes eradicate the virus very effectively in the lab, we need to see if they work on patients and that’s the point of our ongoing clinical trial.
“Importantly, the study will not give us any direct evidence on viral transmission between patients, which would require a different type of study on a much larger scale.
“The ongoing clinical trial, however, will show us how long the effects last after a single mouthwash administration in patients with Covid-19.”
He added: “While this in vitro study is very encouraging and a positive step, more clinical research is clearly needed now.
“We need to understand if the effect of over-the-counter mouthwashes on the Covid-19 virus obtained in the laboratory can be reproduced in patients and we are looking forward to completing our clinical trial in early 2021”.
Dr Nick Claydon, a specialist periodontist, said he believed the research was “very valuable”.
He said: “If these positive results are reflected in the Cardiff University clinical trial, CPC-based mouthwashes such as Dentyl used in the in vitro study could become an important addition to people’s routine, along with hand washing, l ‘physical distancing and the use of masks, both now and in the future. “
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