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The first proven infection with the novel SARS-CoV-2 coronavirus was recorded in New York on March 1, 2020. However, according to current research, the virus has probably a little earlier established there.
This is the result of a research group led by the Austrian virologist Florian Krammer who works there. This research at the Icahn School of Medicine on Mount Sinai in New York and developed one of the first laboratory tests on antibodies to the virus shortly after the onset of the coronavirus pandemic. Now the team is investigating the Review of the trend of diffusion in the city, which was one of the first to be severely affected outside of China.
Corona in New York: Monitoring of diffusion
The research team must monitor the spread of the coronavirus Blood samples from patients from Mount Sinai Hospital examined. The samples are in two groups divided.
The first group includes those patients who were treated in the clinic’s emergency room from February to July. The second group is assigned to those who, for example, passed routine exams there.
After all it was more than 10,000 Plasmaprobenwhich were then tested for antibodies against SARS-CoV-2. Interesting results were shown.
First infections from mid-February
It turned out that the first positive results from the week of 17 to 23 February 2020 it could be detected in the samples of the first group. However, the first infection detected to date was not confirmed until March 1, 2020 in Mount Sinai Hospital registered. Krammer told the Austrian news agency that he was less surprising that the virus was circulating in the internationally connected metropolis of New York earlier than previously thought.
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The rate of positive samples in the first group remained between 1.4 and 3.2 per cent by mid-March. With 62 percent this group reached the Peak of positive samples around April 19th. First Ende Mai then followed on Recession, which then stabilized at just over 20% by July. Values in the second group were significantly lower and reached 20% stable by April 19.
Based on the results and comparisons with other studies, the scientists conclude this By the end of May, about one-fifth – 1.7 million – of New Yorkers had been infected. However, one was far from one Herdenimmunität far. According to the researchers’ estimates, this would require a share of 67 percent with antibodies detected serologically.
One percent mortality
The research team also determines a Infected mortality rate (IFR) of 0.97%. This value is therefore well above the IFR established in 2009 with the outbreak of the H1N1 influenza virus, also known as “swine flu”. According to the researchers, the value at that time was estimated to be between 0.01 and 0.001 percent.
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Florian Krammer attributes the high death rate in New York primarily to “Health system overload” back. There was also one “relatively old population structure”, and you didn’t know how to deal with the completely new virus. As a further reason for the high death rate, Krammer also cites that the population was surprised by this virus because they knew nothing of its existence.
Furthermore, the analysis of the samples showed that the The apparently relatively stable immune defense persists. The number of antibodies to the new virus remains at a higher level for at least five months. It has also been shown that existing antibodies can neutralize a SARS-CoV-2 pathogen. “The antibody response looks ‘normal’ and is relatively stable,” Krammer says. These results are also used in a study in the “Science” magazine shown.
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