[ad_1] Gene modification nucleases such as CRISPR / Cas9 can efficiently create double-stranded breaks at a target locus in the genome. Often, double-stranded breaks are subsequently repaired by non-homologous end-junction mechanisms, leading to insertions and deletions (indel). One strategy, called homology-directed repair (HDR), is used to obtain gene knock-in patterns …
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[ad_1] San Francisco, CA, November 30, 2020 (GLOBE NEWSWIRE) – Taking a major step forward in HIV research, scientists at Temple University’s Lewis Katz School of Medicine have successfully modified SIV, a virus closely related to HIV, the cause of AIDS – from the genomes of non-human primates. The turning …
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[ad_1] Scientists at Trinity College Dublin have developed a new approach to gene therapy that offers one-day promise of treating an eye disease that leads to progressive vision loss and affects thousands of people around the world. The study, which involved a collaboration with clinical teams at Royal Victoria Eye …
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