[ad_1] HMR59 targets geographic atrophy: a severe form of advanced AMD. In geographic atrophy, complement overactivity destroys cells in the macula, the central part of the retina responsible for central vision and fine detail vision, progressing to blindness. Patients with AMD often have low levels of the CD59 protein, which …
Read More »Experimental gene therapy may be effective for MND patients with a recently discovered gene mutation
[ad_1] Researchers from the Neuroscience Institute of the University of Sheffield in the UK have identified a new genetic risk factor for motor neuron disease (MND) in so-called “junk DNA”. The recently discovered genetic changes are present in up to 1% of patients with MND. The research, published in the …
Read More »Gene therapy offers humans with sickle cell disease the possibility of a better future
[ad_1] IMAGE: View of Evie Junior More Credit: UCLA Broad Stem Cell Research Center For Evie Junior, living with sickle cell anemia was like running a marathon. “But it’s a marathon where as you go, the trail gets steeper and then you lose your shoes,” the 27-year-old said. “It gets …
Read More »Penn researchers open the door to the tumor microenvironment for CAR T cells
[ad_1] PHILADELPHIA – The labyrinth of muddled blood vessels in the tumor microenvironment remains one of the most difficult blocks for cell therapies to penetrate and treat solid tumors. Now, in a new study published online today in Nature Cancer, Penn Medicine The researchers found that combining chimeric antigen receptor …
Read More »The basic concepts lay the foundation for personalized immunotherapy
[ad_1] Reviewed by Emily Henderson, B.Sc.November 23, 2020 Personalized immunotherapy for cancer and more introduces personalized immunotherapy with multidimensional analysis models to determine the best immunotherapy plan for patients. The book introduces readers to some basic concepts that lay the foundation for personalized immunotherapy: the development of an important histocompatibility …
Read More »Scientists use gene therapy to regenerate damaged optic nerve fibers
[ad_1] Reviewed by Emily Henderson, B.Sc.November 5, 2020 Scientists have used gene therapy to regenerate damaged nerve fibers in the eye, in a discovery that could help develop new treatments for glaucoma, a leading cause of blindness worldwide. Axons – nerve fibers – in the adult central nervous system (CNS) …
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