[ad_1] Gene modification nucleases such as CRISPR / Cas9 can efficiently create double-stranded breaks at a target locus in the genome. Often, double-stranded breaks are subsequently repaired by non-homologous end-junction mechanisms, leading to insertions and deletions (indel). One strategy, called homology-directed repair (HDR), is used to obtain gene knock-in patterns …
Read More »CRISPR-Cas9 could revolutionize the treatment of some cancers
[ad_1] Recent experiments in cell cultures and in animals provide hope for the potential use of the CRISPR-Cas9 genetic engineering tool for the treatment of certain types of cancer. To understand, we interviewed Anna Gutkin, PhD student in nanomedicine, therapy through RNA, drug administration and co-author of the recent study …
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