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Revision To prescribe presented its new list of one hundred drugs on Thursday “more dangerous than useful“, to be avoided due to health risks”disproportionate“who are managing patients, with newcomers like Propecia against male pattern baldness.
Among those added this year to this blacklist, there are two drugs that expose to adverse effects “disproportionate“in relation to their low efficacy or the benignity of the disorders treated. This is the case of the famous drug against moderate hair loss in men, finasteride 1 mg (Propecia and generics).
The ANSM Medicines Agency has already warned about the risks of psychiatric (anxiety, depression) and sexual disorders (including ejaculation disorders and decreased libido) that should lead to the suspension of this anti-baldness treatment.
Also pinned: piracetam (Nootropyl and generics), a “vasodilator” licensed in various indications including dizziness, and as an adjunct treatment for chronic minor (cognitive or sensorineural) disorders related to aging.
There are three other drugs, which have some effectiveness, but with disproportionate side effects or for which there are other less dangerous options. This is esketamine (Spravato) nasal spray “with very uncertain effectiveness“against depression resistant to antidepressants; pimecrolimus (Elidel not marketed in France) against atopic eczema, but with an increased risk of skin cancer and lymphoma. The third is romosozumab (Evenity, not marketed in France) for severe osteoporosis in postmenopausal women.
Among the drugs to be excluded there are also a dozen drugs of the gliflozin family, against diabetes.
Sore throat, cough, cold … other products not recommended in previous years are still high on the list. The 2021 list covers 112 drugs, 93 of which are marketed in France, he explains To prescribe.
The drugs referred to in this list are “causes of death, hospitalization, or severe or very troublesome adverse effects, largely preventable“, assures the magazine. These are however”not necessarily the future ‘Mediator’, at the center of scandals and trials (…). Especially if all health players react in time“, points out.
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