Scientists find the key gene for cellular aging

All living things are born, live and die. This is one of the most important laws of nature. This process, which proceeds the same in humans, has been studied for a long time. The researchers seem to be starting to get the results of their research. Biological a mysterious gen the researchers who discovered this gene age-related diseases It is intended to use in treatment and improvement.

This discovery made by researchers from the University of Wisconsin-Madison, significantly slowing down biological aging It allows us to reverse it. Work, mesenchymal stem cells (MKH) aims to reverse cellular aging by using rejuvenation.

How has cellular aging been reversed?

Fellow of the faculty and principal investigator of the Department of Biomedical Engineering of the University of Wisconsin-Madison Wan-Ju Li, “HWhile we join previous findings on MSC rejuvenation through cellular reprogramming, our study goes further by providing insight into how reprogrammed MSCs are regulated at the molecular level to enhance the cellular manifestations of aging.“expressions used.

“More importantly, we were able to identify the signaling pathway, which is one of the fundamental mechanisms that control activities related to cellular aging.“Li said,”We believe our findings will provide an understanding of MSC aging and its regenerative importance.“He said they want to largely prevent aging-related diseases by using their expressions.

The research, published this week in the scientific journal Stem Cells, “a very important successResearchers analyzed MCCs from human synovial fluid in the knee and elbow joints. As a result, rejuvenated MSCs were obtained.

In the published article, “We found that aging-related activities were significantly reduced in MSCs compared to those of the parental lineage. This indicates a reversal of cellular aging.” expressions were used. Particularly osteoclasiaStating that the present invention is of fundamental importance in the therapies to be produced to improve cartilage degeneration, Dr. Li, Parkinson and heart disease He said they hoped to benefit from this treatment.