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Coronavirus can cause flu-like symptoms in infected people and can appear in severe forms, and in severe cases, patients can suffer from acute respiratory distress syndrome (ARDS).Acute respiratory distress syndrome), Which can lead to life-threatening pneumonia, multiple organ failure, septic shock, and death.
Male hormone
Is there a link between testosterone levels and severe cases of Corona?
In an article recently published in a magazine Medical hypotheses Researchers from the United States of America and Saudi Arabia have described the direct relationship between testosterone levels, inflammatory cytokines, disease progression and worse outcomes in Corona male patients.
The path of entry of the main Corona virus through the mucous membranes of the nose depends on the use of ACE receptors, as enzyme receptors play an important role in lung protection and viral binding to these receptors.
Since the ACE receptor is also expressed in testis cells as a primary product, this affects testosterone secretion in male Corona patients.
Corona patients, suffering from low levels of the hormone testosterone, have been reported to have developed severe symptoms requiring ventilator support, due to the high risk of lung damage.
Males usually have 7-8 times higher testosterone levels than females, and studies have already shown that corona affects men far more than it affects women, as the death rate in men is double the rate of mortality in patients with female crown.
The effect of low testosterone levels in male patients
Low testosterone levels in critically ill male patients negatively affect the work of endothelial cells and improve the defective immune response, and also affect the ability to remove the virus, and therefore low blood testosterone levels are a weak prognostic indicator for patients males with Corona.
Based on these findings, the authors speculate that lower testosterone levels are directly related to disease severity and worse clinical outcomes in male coronavirus patients.
Several studies have reported the relationship between a gradual decline in testosterone levels and severe lung complications leading to ICU admission, assisted ventilation, and worse disease outcomes.
On the other hand, high testosterone levels are said to lead to blood clotting which is another deadly manifestation of Corona patients, this makes a critical assessment of testosterone levels in the blood and its importance in the development of the disease Crown This is crucial for re-evaluating treatment strategies.
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