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Brazilian researchers have reported two cases of coronavirus-infected people having mild symptoms, passing on the infectious virus for a longer period than previously reported. The researchers say according to the pre-press site medRxiv The results, not yet examined, indicate that individuals with mild symptoms may remain contagious for long periods, highlighting the need for them to take adequate precautions to avoid spreading the virus to others.
Patients who had mild but long-term symptoms of coronavirus disease still had virus recurrence, up to 37 days (in case 1) and 24 days (in case 2) after symptoms appeared.
Patients with Mild Corona
What have studies shown so far?
Since the beginning of the epidemic COVID-19 For the first time in Wuhan, China, at the end of last year (2019), research indicated that the virus can be detected among infected individuals one to 3 days before symptoms appear.
Viral load peaks within the first week of symptoms before it gradually decreases over time, and studies have estimated that the virus capable of replicating is no longer present in patients with COVID-19 20 days after the onset of symptoms.
What did the current study include?
Now, the team from the University of Sao Paulo has shown that in two Coronavirus-infected women with mild disease, the virus has been shown to be able to replicate for a longer period than previously reported.
The first case (Case 1) of a woman in her 50s reported in mid-April that she experienced dry cough, headache, loss of strength, joint pain and muscle aches for the first time, but without fever, 20 days earlier.
After 22 days of the onset of symptoms, a swab was taken from the nasopharynx of a woman who tested positive for Coronavirus, then the woman developed nausea, vomiting and loss of the sense of taste and smell.
Significant symptoms persisted and 37 days after the onset of symptoms, a second throat swab was tested positive for the virus, and although the woman was still reporting a mild headache and loss of strength in mid-May, most of the symptoms it gradually disappeared.
The second woman (case 2), who is also 50 years old, reported having fever, headache, sore throat, cough, loss of strength, joint pain, muscle aches, nasal fluid discharge and nausea at first. of May.
A nasopharyngeal swab test was performed 5 days after symptoms appeared and tested positive for Corona, and after symptoms persisted, a second throat swab was taken 24 days after symptoms appeared, which showed the woman she was still infected, and case 2 remained symptomatic for 35 Almost a day after it appeared.
According to WHO recommendations (WHOAs for the criteria for discharging coronavirus individuals from isolation, patients should recover clinically and be symptom-free, the researchers say, and write, “Our data confirms that even individuals with mild symptoms can be contagious.” .
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