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Blood tests could someday detect patients at risk of developing Alzheimer’s disease by measuring the levels of two molecules in their blood, according to preliminary research released Monday.
Depending on the concentration of these two molecules, called ptau 181 and NfL, we could predict future progression of Alzheimer’s disease in individuals with mild cognitive impairment, according to this work published in the specialist journal Nature Aging.
The Swedish and British researchers base their conclusions on examining data from around 570 patients. The experimental test was able to predict the development of Alzheimer’s patients with an accuracy of 88% over a four-year period.
There is no cure for this disease, which results in brain degeneration and memory loss. In recent years, several experimental studies have given hope for progress in its early diagnosis, which has not yet translated into concrete progress in real life.
” If these blood markers can predict the onset of Alzheimer’s in larger, heterogeneous groups, we could see a revolution. “Hoped Richard Oakley, head of research within the Alzheimer’s Society charity, quoted by the UK’s Science Media Center (SMC).
For Musaid Husain, professor of neurology at Oxford University, this advantage could ” potentially revolutionary “. ” These findings need to be confirmed but in the context of other recent work, it could be an important step towards early diagnosis as well as testing new treatments in a less advanced stage of the disease. “He went on, quoted by the SMC.
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