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THE ESSENTIAL
- The two combined studies, involving nearly 23,000 people, indicate that the plant-based vaccine tested is not only safe, but also comparable in effectiveness to current flu vaccines.
Two Lancet studies reveal the efficacy of a herbal flu vaccine, a previously unprecedented initiative. Since the flu virus is constantly mutating, vaccine designers have to renew their formula every year (hence the need for frail people and healthcare professionals to be vaccinated annually). “Plant production may exceed some of the limitations of current vaccines” against the flu, explain the scientists in the preamble.
Absolute efficiency
Two studies were conducted in parallel: one in adults aged 18 to 64 and the other in people aged 65 and over. The first search was carried out on 73 sites and the second on 104, all located in Asia, Europe or North America.
Regarding the study on young people aged 18 to 64, the criteria for inclusion in the cohort were body mass index (less than 40 kg / m 2), age and general good health. In the over 65 study, the criteria for selecting participants were body mass index (35 kg / m 2 maximum), age, absence of acute or progressive medical problems, and waist position (excluding people residing in an Ephad or a specialized health institution).
With: “the main finding of the 18-64-year-old study was the absolute efficacy of the vaccine in preventing laboratory-confirmed respiratory diseases caused by influenza strains,” the scientists write. They continue: “The main finding of the over 65 study was the relative effectiveness of the vaccine in preventing laboratory-confirmed influenza-like illnesses caused by any flu strain.”
23,000 people tested
In other words, the two combined studies, involving nearly 23,000 people, indicate that the plant-based vaccine tested is not only safe, but also comparable in efficacy to current flu vaccines. “To our knowledge, these studies and the clinical development program that preceded them constitute the largest demonstration to date of the potential of a plant-based vaccine for humans,” conclude the researchers.
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