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According to the NTV news; A new experimental type of coronavirus vaccine containing nanoparticles has been developed by the Washington University School of Medicine in the United States. It aims to create immunity against Covid-19 by infecting cells with nanoparticles capable of mimicking more than 60 mutations of the new type of Coronavirus (SARS-Cov2).
Scientists announced that in the vaccine experiments on mice, the number of antibodies that neutralized the coronavirus was seen to increase by 10 times.
It can protect 10 times from future mutations
The vaccine was tested on a macaque monkey after mice. The researchers said the vaccine is trained in different forms of the spike proteins that allow the coronavirus to attach to cells and said it neutralizes all the different coronavirus mutations given to the monkey. Therefore, it has been claimed that the vaccine containing nanoparticles could protect people from other mutations that could arise in the future of the Coronavirus.
Doctor, one of the authors of the study published in the scientific journal “Cell” Neil King“We hope that the vaccine we have developed in the form of nanoparticles will play an important role in the fight against the pandemic that causes so much damage in the world. Our results are very promising. We hope to start human trials as soon as possible. The new technologies they offer us great opportunities for the disappearance of apparently hopeless diseases. ” used expressions.
However, it has been announced that human testing of the vaccine will begin later this year and negotiations are underway between the university and the two biotech companies for mass production.
It was also noted that the vaccine does not require cold chain supplies such as Pfizer7Biontech, Moderna, and AstraZeneca / Oxford vaccines, which are currently pursuing their final human tests. Scientists said the vaccine can be accessed safely anywhere in the world thanks to the convenience of storage conditions.
In order for a vaccine to be widely used, it must be tested in humans in 3 steps. In the first phase of clinical trials, the safety of the vaccine and possible side effects are studied on a small number of healthy volunteers. In the second phase, the effectiveness of the vaccine, whose reliability has been confirmed, is tested on more than 100 subjects. In the third and final stage, the same process is repeated with thousands of subjects. The whole process can take months or even years.
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