The study warns of new pediatric cardiovascular diseases


A European study on the cardiovascular effects of novel coronavirus infection in children and adolescents revealed the existence of a “multisystem inflammatory syndrome”.

The second world journal with the greatest impact on Cardiology, Circulation, recommends this article to all pediatricians resulting from a multicentre study, that is, to which several research centers have contributed.

The authors of the study, coordinated by the Virgen del Rocío University Hospital in Seville, analyzed the most frequent cardiovascular manifestations in multisystem inflammatory syndrome (MIS-C), a new disease that was described after the outbreak of the pandemic in pediatric patients.

The peak incidence of multisystem inflammatory syndrome in Europe was recorded just before summer, and researchers revealed that cardiovascular manifestations can often appear in a previously healthy population.

The study also concludes that children with pediatric multisystem inflammatory syndrome should have specific follow-up to rule out cardiovascular manifestations, such as shock, cardiac arrhythmias, pericardial effusion and coronary arterial dilation.

These were the four most common cardiovascular complications described.

The good news is that, compared to adults, mortality in children with the syndrome is rare, despite a significant increase in biochemical markers of inflammation or multisystem involvement.

However, there is a statistically significant correlation between the degree of elevation of biochemical markers and the need for support in the ICU, the study concludes.

55 European centers and 286 children participated in this research, the largest sample of pediatric patients in the world to date, which reveals the most complete clinical cardiovascular picture including data on its clinical presentation.

The article, whose first author is Israel Valverde, head of Pediatric Cardiology at the Seville hospital and researcher in the IBiS Cardiovascular Pathophysiology group, also includes laboratory markers, cardiac imaging abnormalities, and the progression of these markers during hospitalization.

According to the editors of the journal, it is of interest to medical specialists around the world and, in particular, to pediatricians in countries now facing a second wave, to know the conclusions of this study considering that they help to understand cardiovascular and clinical manifestations. to optimize therapy.

The Virgen del Rocío Pediatric Intensive Care Unit also participated in this study and, in total, more than 100 researchers from 17 European countries and 48 cities collaborated.

In May, the existence of this syndrome associated with covid-19 disease had already been reported from the Netherlands, but the first cases had been reported in April in the UK.

Similar case reports have been followed in countries such as Ireland, Belgium, Switzerland, Italy, Spain, France, the United States and Portugal.


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