Swiss molecular biologists have created an analog of the heart of a mouse embryo from stem cells.
The main advantage of embryonic organelles is that many different tissues develop parallel within them. They exchange the same fundamental signals for the correct growth of the embryo. The heart cells that grow in them are in the same environment they would be in a real embryo.
Juliana Rossi, molecular biologist at the Swiss Federal Polytechnic and one of the authors of the work.
Experiments with universal stem cells have been going on for several years: scientists have already tried to cultivate, for example, a liver analogue with their help.
Rossi’s team has taken the first big step towards in vitro organ culture.
A team of scientists analyzed the sets of signals needed for stem cells to start converting into specific tissues in the body. And the heart is the first organ that is formed within the embryo of multicellular organisms. As a result, the researchers decided to grow not a full-fledged heart, but its embryo.
The finished organ, which turned out as a result of the work, began to contract, and also to generate and perceive signals characteristic of a developing heart. It is also noted that the blood vessels began to grow around the organ.
The work continues, the scientists intend to improve their developments to grow a human heart in the future.