Tag Archives: genetic editing

Modifying Cas9 can improve the efficiency of gene editing

[ad_1] Gene modification nucleases such as CRISPR / Cas9 can efficiently create double-stranded breaks at a target locus in the genome. Often, double-stranded breaks are subsequently repaired by non-homologous end-junction mechanisms, leading to insertions and deletions (indel). One strategy, called homology-directed repair (HDR), is used to obtain gene knock-in patterns …

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CRISPR-based therapy shows early promise for cancer

[ad_1] November 23, 2020 – Researchers say they used CRISPR, a new technology that allows scientists to modify a cell’s DNA, to destroy cancer cells in mice. The first research conducted on two types of metastatic cancer – ovarian cancer and brain cancer – have not been tested in humans. …

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