Potential Herpes Virus Vaccine Shows Promise – News



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Immunization was developed by US scientists and could become the first for this disease, which affects approximately 4 billion people worldwide.


A vaccine against herpes development in the United States has shown good results in animal testing.

The study, published in the scientific journal Nature Vaccines, reports that immunization resulted in a significant increase in antibodies in guinea pigs.

The immunizing potential uses a genetically modified form of the herpes simplex virus, which has been altered to prevent the agent from taking refuge in the nervous system.

When the animals were infected with a virulent strain of the herpes simplex virus, those who had been vaccinated had fewer genital lesions, less viral replication, and less viral spread.

Also read: Herpes virus can accelerate Alzheimer’s disease, research says

The virus used in the study is a herpes simplex virus type 1 (HSV-1), best known for causing cold sores around the lip. However, demonstrated immunity is also capable of reducing the incidence of type 2 (HSV-2), which is sexually transmitted.

According to the WHO (World Health Organization), 3.7 billion people (67%) in the world live with HSV-1, in addition to about 490 million who are carriers of HSV-2.

The two strains of the virus cause lesions on the skin: they can become blistering and painful ulcerations in the mouth or genital region, mainly. Most HSV-1 infections are acquired in childhood and the infection lasts a lifetime.

The virus can be reactivated multiple times when the person has, for example, a fever, menstruation, emotional tension, or some kind of suppressed immune system.

Although the viruses that cause common herpes have been around endemically for over four decades, no vaccine has been created to date.

The vaccine project is led by researchers from the University of Cincinnati, Northwestern University and the University of Nebraska-Lincoln, with support from the National Institutes of Health (NIH) in the United States.

Herpes can be contracted in poorly washed glasses. Understand the disease:

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